(My apologies! (Another CFS moment…) The last blog contained a draft on the first story – not the completed version. Thanks for your patience….)
When it rains it pours. Events regarding XMRV, Dr. Mikovits and the WPI have come hot and heavy during the last week.
WPI’s Civil Lawsuit Against Dr. Mikovits – First some background. Dr. Mikovits was terminated from the WPI in late Sept for refusing to share a cell line with Dr. Lombardi. According to spokesperson from the WPI’s legal team Dr. Mikovits was terminated not because she refused to share her cell line with Dr.… Read More
In Part II of the XMRV section of the conference we look at the Coffin/Mikovits presentations, Hanson’s update on her XMRV work and look at the recent XMRV research findings.
The pMLVs Strike Out – Hanson Disavows Former Results
“The sensitivity of the PCR assays used requires extreme caution in interpreting results
Dr. Maureen Hanson”
Background – Dr. Hanson’s was one of two labs (Lo/Alter) to find not XMRV but closely related murine leukemia viruses called pMLV’s, in CFS blood samples. Dr. Mikovits heralded the findings as proof that a family of murine leukemia viruses were present in chronic fatigue syndrome but the their similarity to endogenous retroviruses raised a red flag.… Read More
Dr. Judy Mikovits has had a difficult couple of months. First the BWG study indicated the tests she developed for XMRV were not valid, then evidence of contamination resulted in a partial retraction of the original Science paper, then she was accused of doctoring a photo at a conference and in the original Science paper prompting several investigation, then she was terminated from her job at the WPI, then she was served with a lawsuit claiming that she had stolen data from the WPI and since last week, she’s being in the Ventura County jail waiting arraignment as a fugitive from justice.… Read More
A New Center – Much research and discussion now is not centered around XMRV but around a prostate cancer cell line called 22RV1. More than anything else this cell line that is what is causing problems for XMRV.
The 22RV1 cell line was created in 1999 in response to a need to study prostate cancer – a major cause of male mortality. Creating the cell line involved ‘passaging’ prostate cancer cells through nude mice tissues. At some point researchers were able to create a ‘cell-line’, a group of cells they could use to reliably grow prostate cancer cells and study them.… Read More