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I had the 23 and Me genetic testing done and ran the raw data through both Genetic Genie and Livewello. I noticed that my MAO A - R297R came back different. Genetic Genie gave me a +/+ and Livewello gave me a
-/-. There is a little side note on Genetic Genie that states they "report the wild types as the defective variant as doctors have clinically observed that patients with methylation problems (especially those of Autism) often have trouble breaking down neurotransmitters. The high activity version of MAO A (which is represented as -/-) can contribute to major depressive disorder."
I keep reading this and my foggy brain is just not getting it. Do I have a mutation that I need to address or not? Please, would someone help to clarify this for me? Any help would be greatly appreciated.
-/-. There is a little side note on Genetic Genie that states they "report the wild types as the defective variant as doctors have clinically observed that patients with methylation problems (especially those of Autism) often have trouble breaking down neurotransmitters. The high activity version of MAO A (which is represented as -/-) can contribute to major depressive disorder."
I keep reading this and my foggy brain is just not getting it. Do I have a mutation that I need to address or not? Please, would someone help to clarify this for me? Any help would be greatly appreciated.