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Autonomic/cardiovascular regulation and cognitive deficits

Marco

Grrrrrrr!
Messages
2,386
Location
Near Cognac, France
Thought this might be of general interest.

It discusses cardiovascular abnormalities and cognitive deficits and how they might be linked in patients with spinal cord injury (SCI) but as most of the literature is from the non-SCI population it applies more broadly.

Interesting that both chronic or episodic low blood pressure/orthostatic intolerance and chronic or episodic increased resting heart rate/arterial stiffness are both associated with various (familiar) cognitive deficits (plus fatigue)

Decentralized cardiovascular autonomic control and cognitive deficits in persons with spinal cord injury

"Cognitive deficits in the areas of memory, attention and processing speed, and executive function are prominent in individuals with SCI, regardless of the level of injury. It has generally been assumed that these cognitive deficits are, in large measure, accounted for by concomitant TBI or pre-morbid conditions.

However, the growing body of evidence to support associations between cognitive deficits and adverse cardiovascular and cerebral vascular changes in the non-SCI literature may be extrapolated to the SCI population."


http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595971/