I am wondering if dessicated thyroid has an effect on sirtuin activity. The first part of the following probably won't appear to have much to do with ME/CFS but bear with me until the end because I think that it might be useful to some people with ME/CFS.
6 years ago my son with schizophrenia started taking dessicated thyroid. We were hoping that it would help him to be able to stop taking so many energy drinks because we knew that they made his symptoms worse and we had seen some studies where people with schizophrenia were benefited by taking thyroid. Some months later he actually went off medication and was doing well, but for some reason I didn't connect it with the thyroid, maybe because I didn't realize that he was still taking it in large doses. After some weeks he ran out and later his symptoms returned but we didn't know why at the time.
Recently he started telling me that he remembered running out of the thyroid before he relapsed and he actually got some dessicated thyroid himself and started taking it and it seems to be helping him. I am pretty sure now that the dessicated thyroid helps him.
Thyroid as a treatment for schizophrenia has never caught on, apparently because no one has any idea of how it could possibly help because the people in the studies had normal thyroid levels and also, it only helped about 45% of the people in the study. Besides this, there isn't really a lot of money in dessicated thyroid so there is less interest in funding studies on it.
I have been thinking about how thyroid could possible help in the light of my hypothesis and what I have learned lately about the methylation of histone tails and one interesting thing is that dessicated thyroid appears to help both under and overmethylated people, since according to Bill Walsh paranoid schizophrenia is a sign of overmethylation and my son is definately undermethylated, yet there are many reports of people with paranoia who are helped by dessicated thyroid.
This web page has a list of things that can supposedly be treated with Armour thyroid and the list not only includes ME/CFS and schizophrenia but quite a few other conditions that cover a pretty wide range of symptoms. (I have no idea where they got their information) This is leading me to consider whether dessicated thyroid has an effect on sirtuins because it appears that sirtuins can have a wide range of effects and if thyroid has a normalizing effect on them in people with these illnesses, well, all I can say is that would be incredible, even if it only helps 45% of the people affected.
Has anyone here tried rather large doses of dessicated thyroid? The range listed in the SZ study was 120 to 1200 mg per day but most of them took no more than 600 mg per day, and my son is taking a little over 600 mg of dessicated thyroid a day right now. (This is dried thyroid, not some chemical component of thyroid.)
6 years ago my son with schizophrenia started taking dessicated thyroid. We were hoping that it would help him to be able to stop taking so many energy drinks because we knew that they made his symptoms worse and we had seen some studies where people with schizophrenia were benefited by taking thyroid. Some months later he actually went off medication and was doing well, but for some reason I didn't connect it with the thyroid, maybe because I didn't realize that he was still taking it in large doses. After some weeks he ran out and later his symptoms returned but we didn't know why at the time.
Recently he started telling me that he remembered running out of the thyroid before he relapsed and he actually got some dessicated thyroid himself and started taking it and it seems to be helping him. I am pretty sure now that the dessicated thyroid helps him.
Thyroid as a treatment for schizophrenia has never caught on, apparently because no one has any idea of how it could possibly help because the people in the studies had normal thyroid levels and also, it only helped about 45% of the people in the study. Besides this, there isn't really a lot of money in dessicated thyroid so there is less interest in funding studies on it.
I have been thinking about how thyroid could possible help in the light of my hypothesis and what I have learned lately about the methylation of histone tails and one interesting thing is that dessicated thyroid appears to help both under and overmethylated people, since according to Bill Walsh paranoid schizophrenia is a sign of overmethylation and my son is definately undermethylated, yet there are many reports of people with paranoia who are helped by dessicated thyroid.
This web page has a list of things that can supposedly be treated with Armour thyroid and the list not only includes ME/CFS and schizophrenia but quite a few other conditions that cover a pretty wide range of symptoms. (I have no idea where they got their information) This is leading me to consider whether dessicated thyroid has an effect on sirtuins because it appears that sirtuins can have a wide range of effects and if thyroid has a normalizing effect on them in people with these illnesses, well, all I can say is that would be incredible, even if it only helps 45% of the people affected.
Has anyone here tried rather large doses of dessicated thyroid? The range listed in the SZ study was 120 to 1200 mg per day but most of them took no more than 600 mg per day, and my son is taking a little over 600 mg of dessicated thyroid a day right now. (This is dried thyroid, not some chemical component of thyroid.)
