I have come to the conclusion after many years of living with CFS that my use of Adderall (a potent amphetamine) greatly offset my gaba glutamate balance. I dont' know if taking traditional supps that help with this will be enough. Has anyone been able to rebalance this or have they ever used an prescription NMDA blocker to address this?
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Gaba/Glutamate balance, NMDA Blocker
- Thread starter Bdeep86
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adreno
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I find magnesium threonate to be very effective.
heapsreal
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Memantine is an nmda antagonist. can help control inflammatory cytokines as well as increase dopamine.
adreno
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Yes, it's significantly more effective than other forms of Mg.
heapsreal
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i have used a low dose memantine 5-10mg and did find it help energy and cognitive aspects. I only use it for a few days and then take a break from it as i think the effects build up.
From what i have read it blocks inflammatory cytokines such as tnf alpha which many cfsers are high in, but the only way to know is to try things??
From what i have read it blocks inflammatory cytokines such as tnf alpha which many cfsers are high in, but the only way to know is to try things??
I have a major GABA/glutamate imbalance due to ativan withdrawal. I have to be extremely careful about what I take because of extreme sensitivity but the only thing I have used which is safe and shows any effect is L-Theanine. GABA doesn't seem to cross the BBB and I have never used a glutamate inhibitor.