Convergence was the word indeed as enterprising researchers dug deep into blood samples kept in the deep freeze for almost a decade to show how immune, metabolic and gut issues may be combining together to produce exercise induced post-exertional malaise in ME/CFS.
Solving this disease is going to require finding ways to connect these different systems. This study is particularly intriguing because it was able to show how energy production problems could effect the gut and the immune system.
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Convergence – How Gut, Immune and Metabolic Issues May be Producing PEM in ME/CFS