RNase L is an enzyme found in all cells that is involved in pathogen defence, apoptosis (cell suicide), muscle cell differentiation, cell migration and many other activities.
The following articles on the topic were written by Cort Johnson and form part of the Phoenix Rising research archive.
At the time of writing, he wrote: “In most CFS patients thus far studied the RNase L enzyme is broken up into pieces. An RNase L fragment commonly seen in CFS patients is the closest thing to a biomarker yet found for this disease.”
- A Guide to RNase L and Chronic Fatigue Syndrome (ME/CFS) (2003, updated 2004) A chapter by chapter synopsis of the 2002 book, “Chronic Fatigue Syndrome: A Biological Approach”.
- A Guide To RNase L in Chronic Fatigue Syndrome (ME/CFS): Background (2003) A deeper look at the IFN induced enzymes (2-5OAS, RNase L and PKR) dysfunctional in CFS.
- Overviews of Papers on RNase L (2003, updated 2004) Synopses of papers published in scientific journals that explore the extent and ramifications of RNase L problems in ME/CFS.