Research into the brain is a key area of ME/CFS research.
The following articles were written by Cort Johnson and form part of the Phoenix Rising research archive.
- The Fatigue in Chronic Fatigue Syndrome (ME/CFS) – Is it Central? (2007) An examination of whether the fatigue in ME/CFS arises in the brain (‘centrally’) rather than in the muscles or other tissues.
- Choline on the Brain? A Guide to Choline in Chronic Fatigue Syndrome (2005) An investigation of whether increased choline levels contribute to cognitive dysfunction and reduced ATP levels impair aerobic metabolism and contribute to the exercise intolerance seen in CFS.
- A Neurological Channelopathy in Chronic Fatigue Syndrome (ME/CFS)? (2005) Damaged ion channels can occur in any cell in the body and so a channelopathy could cause vastly different symptoms depending on which tissues it occurred in. Recent ME/CFS gene expression studies have highlighted several ion channel genes.
- Do Chronic Fatigue Syndrome (ME/CFS) Patients Have a Selfish Brain? (approx. 2005) Examination of a theory that the brain sometimes takes energy that should be used by the muscles and fat tissues, and the relevance of this to ME/CFS.
- Proteins on the Brain: Spinal Tapping for ME/CFS (2010) A discussion of an attempt to find a protein signature for ME/CFS in spinal fluid.