Adderall (Amphetamine & Dextroamphetamine)

Adderall  (Amphetamine & Dextroamphetamine) is

a ‘pyschostimulant’ amphetamine. Introduced in 1996 Adderal is primarily used to treat attention deficit disorder and narcolepsy and treatment resistant depression but has also been used off-label for weight loss. Adderall increases energy levels and concentration. It is believed to increase dopamine, serotonin and norepinephrine levels.

Adderall May Work in Chronic Fatigue Syndrome (ME/CFS) Because

it increases energy levels and concentration. It may increase the levels of some key nervous system agents (neurotransmitters) that may be low in ME/CFS.

Chronic Fatigue Syndrome (ME/CFS) Physicians Report

Dr. Bateman uses both Ritalin and Adderall but prefers Adderall. She reports Adderall also helps with pain and has been a drug that has enabled some patients return to work. On the other hand others can’t stand it. She reports that acute onset patients with flu-like symptoms don’t seem to do as well on Adderall.


Adderall is available in single or extended release forms. Dr. Bateman recommends 5-30 mg. 2-3x’s a day of Adderall. The IACFS/ME Treatment Primer suggests 5-10 mgs, 3x’s a day.

Side Effects (not complete)

include dry mouth, insomnia, bad breath, weight loss, tolerance and addiction. Adderall is a Schedule II drug that requires frequent doctor visits because of its potential for addiction if misused. Dr. Bateman states she has never had a problem with this. The IACFS/ME Treatment Primer states tolerance may develop if used daily.

This summary was put together by a layman with ME/CFS and is not intended to provide complete information on the side effects or any other aspects of this drug. It is for informational purposes only.



Lucinda Bateman, MD., 2006. “Tips and Travails of Treatment”, An abridged version of a seminar transcript of a Nov. Lecture in Auckland, New Zealand, by Pat Fero and David Thompson.

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