Andrew Gladman explores the current and historic hypotheses relating to nitric oxide problems in ME/CFS. This second article in a 2-Part series puts nitric oxide under the microscope and explores what it is, what it does and why it is so frequently discussed in the world of ME/CFS. The focus of this article is to build upon the previous article and explore how the
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Andrew Gladman explores the current and historic hypotheses relating to nitric oxide problems in ME/CFS. Part 1 of a 2-part series puts nitric oxide under the microscope and explores what it is, what it does and why it is so frequently discussed in the world of ME/CFS. Part 1 focuses on what nitric oxide is, how its produced and what exactly
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Andrew Gladman brings our coverage of the Understanding & Remembrance Day for Severe ME, airing the voice of patients … Long, lazy August afternoons. The sun is shining, the birds are singing, the garden growing, and the children are free from school. For many this time of year means holidays, family get-togethers, and a period of general relaxation. However, for sufferers of
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Andrew Gladman puts hyperparathyroidism under the microscope, exploring what the disease is, how it can mimic ME/CFS in presentation and how it is treated. Chronic fatigue syndrome or ME/CFS is, whether we like it or not, by current definition a diagnosis of exclusion. The biggest diagnostic task is therefore differentiating it from the plethora of other disorders that also have
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Andrew Gladman muses upon what lessons he has taken from two years of ME/CFS. If you’re aware of my previous articles here at Phoenix Rising then it’s pretty clear that I don’t generally spend my time musing upon the philosophy of the disease. I find it better to spend my time reading research and trying my best to break it
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Andrew Gladman reflects upon the recent IACFS/ME conference and the buzz surrounding a small molecule, leptin. It’s safe to say that the past couple of weeks, following the IACFS/ME 2014 conference, have been something of a whirlwind in terms of new ME/CFS research being unveiled. Now that the dust has had a chance to settle let’s take a step back
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The second in a new series of ‘In Brief’ articles, where Andrew Gladman provides a helpful insight into the science behind fairly common topics, exploring how they relate to ME/CFS. This time he discusses the adrenal glands and why they can be such a talking point … While the frequent topics of conversation relating to ME/CFS appear to now be
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In the first in a new series of ‘In Brief’ articles, Andrew Gladman provides a helpful insight into the science behind fairly common topics and explores how they relate to ME/CFS. This time he looks at the muscles, exploring how our reported symptoms might be associated with our condition and considers why such problems could occur… When ME/CFS is discussed,
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Andrew Gladman considers the importance of dysautonomia and several of its component parts — neurally mediated hypotension, inappropriate sinus tachycardia and postural orthostatic tachycardia syndrome — all recognised as problematic comorbidities by ME/CFS patients … Dysautonomia, most commonly experienced as postural orthostatic tachycardia syndrome (POTS), is a recognised comorbidity of ME/CFS. There is little debate surrounding this and much research
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In the second and final part of Andrew Gladman’s journey, he finally receives the diagnosis that best seems to fit his symptoms, but as his health shows no sign of improving, he reluctantly decides to withdraw from his biochemistry degree and spend more time to try and reach an accommodation with his illness… “It was early November 2012 and I
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Andrew Gladman takes a brief look at what cytokines are and how they might relate to our disease – exploring some of the research that is indicating their involvement in disease pathways… In recent years ME/CFS research has turned the spotlight on several areas, such as autoimmunity, the cardiovascular system and the autonomic nervous system. While it is fair to
Continue It has been a devastating twelve months for Andrew Gladman after he took well meant advice to ensure his vaccinations were up-to-date. He was ready to begin study at university, but the vaccines seem to have led to some very obvious and bad reactions that did not immediately resolve. It appears that this trigger, not uncommon among a significant minority
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