The idea that an undiagnosed EBV infection causes or contributes to CFS is controversial. This type of argument – that inadequate diagnostic procedures prevent researchers from identifying the pathogens causing or contributing to ME/CFS – is frequently made by advocates of the idea that a chronic infectious state is present in CFS. It may seem incongruous that researchers in the
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ME/CFS Buzz (March 12th 2012)
Posted by Cort Johnson RESEARCH GROUPS ON THE MARCH….. CAA Spells Out Approach in Research Ist Webinar I believe we are at the cusp of a revolution in how CFS is viewed, researched and treated. I don’t know it’s a year or 5 years but the future has never been brighter. Kim McCleary With 471 people enrolled, participation in a
ContinueCDC CFS Program Changing Its Stripes, NIH Lags Behind in 2012
Posted by Cort Johnson After looking at private/non-profit research efforts in 2012 we turn to what the Feds (CDC, NIH, DOD) will be doing…. Centers for Disease Control The CDC approach to ME/CFS under Dr. Unger is changing and for the better. Increased outreach and collaboration have become hallmarks of Dr. Unger’s CFS CDC program. Physician Education Three Continuing Medical
ContinueTrends in Chronic Fatigue Syndrome Research
This paper examines the quantity and focus of CFS research over time and draws some conclusions regarding their implications for CFS patients. Background After CFS burst upon the scene in the mid eighties it didn’t take it long to become a major research topic. The first study PubMed cites on CFS (in the 1980’s) was published in 1987* and by
Human Herpes Virus 6 (HHV-6) and Disease
HHV-6A and B: Two Variants or Two Viruses? For years HHV-6A was believed to simply be a variant of HHV-6. Increasing evidence suggests, however, that not only does HHV-6A vary from HHV-6B but that it is very different indeed: differences in mode of transmission, prevalence, types of infection, types of cells infected etc. suggest to some researchers that it’s only
The Pharmacogenomics Studies on Chronic Fatigue Syndrome (ME/CFS) III: The Gene Expression Studies
These three studies were the largest and most complex studies done yet in CFS. Redefining gene expession in CFS? Broderick, G., Craddock, R., Whistler, T., Taylor, R., Klimas, N. and E. Unger. 2006. Identifying illness parameters using classical projection methods. Pharmacogenomics 7, 407-416. This is the largest gene expression study yet done. The amount of data the researchers were presented
Glutathione Depletion-Methylation Cycle Block: A Hypothesis For the Pathogenesis of Chronic Fatigue Syndrome by Richard A. Van Konynenburg Ph.D.
Independent Researcher and Consultant, (richvank@aol.com) INTRODUCTION AND HYPOTHESIS. At the Seventh International Conference of the AACFS in 2004, the author proposed and defended the hypothesis that glutathione depletion is an important part of the pathogenesis of CFS (1). In the conclusions of that paper it was noted that it seemed likely that there are vicious circle mechanisms involved in CFS
Is Glutathione Depletion an Important Part of the Pathogenesis of Chronic Fatigue Syndrome? by Richard Van Konynenburg (Independent Researcher)
Presented at AACFS Seventh International Conference Madison, Wisconsin, October 8-10, 2004 What is glutathione? [Refs. 1-5] • A tripeptide composed of the amino acids glutamic acid, cysteine, and glycine. Its molecular weight is 307.33 Da. • Found in all cells in the body, in the bile, in the epithelial lining fluid of the lungs, and, at much smaller concentrations, in the blood. •
Choline on the Brain? A Guide to Choline in Chronic Fatigue Syndrome
(This paper largely follows the outline of a paper by Chaudhuri and Behan that examined magnetic resonance studies on CFS (Chaudhuri and Behan 2004). Brain metabolic activity in CFS Three studies have examined metabolic functioning in the brain using proton magnetic spectroscopy (MRS) (Chaudhuri et. al. 2003, Tomoda et. al. 2000, Puri et. al. 2002). The levels of three metabolites
XMRV Information Center
THE XMRV INFO CENTER Info Information Center XMRV Buzz – The Latest News Resource Center Ongoing XMRV Studies Discuss It Testing, Treatment and Transmission Testing Treatment Transmission Blogs and Articles Clinical Director Dr. Deckoff-Jones Talks On the WPI’s Clinic Dr. Mikovits in Sweden: New Findings in XMRV Retrovirology Publishes 5 Papers on Contamination A Draw at
ME/CFS Buzz: News of the Week From Phoenix Rising (Feb 29th, 2012)
Posted by Cort Johnson ME/CFS Buzz: News of the Week – a New Feature From Phoenix Rising (weekly short takes on ME/CFS research, treatment and news) RESEARCH Fear and Loathing….An Exercise Study Kinesiophobia, catastrophizing and anticipated symptoms before stair climbing in chronic fatigue syndrome: an experimental study.Nijs J, Meeus M, Heins M, Knoop H, Moorkens G, Bleijenberg G. Nijs
Continue2012 – the Year Ahead Pt II: ME/CFS Efforts Expand
Posted by Cort Johnson Discuss this article on the forums Background The theme of this year is expansion, not contraction as one might expect after the biggest finding in CFS history (XMRV) didn’t pan out. With XMRV drawing more attention than ever to this disease the ME/CFS research community emerged in better shape with more new projects and more new
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