Glutathione and the Methylation Cycle by Rich Von Konynenburg Ph.D
Rich Van Konynenburg proposed that methylation blockades played a key role in chronic fatigue syndrome and autism and created a popular treatment protocol for ME/CFS
Rich Van Konynenburg, Ph.d., an independent researcher, believed glutathione depletion causes many of the problems in ME/CFS. The master anti-oxidant in the body, glutathione also plays a role in amino acid transport, protein synthesis, the cell cycle and immune cell proliferation.
These papers by Rich Van Konynenburg examine ways to enhance glutathione, detoxification and energy production in ME/CFS.
Rich died unexpectedly in his sleep on Sept 25th, 2012.
TREATMENT PAPERS
- Treating Glutathione Depletion-Methylation Blockades in CFS Pt I: The How’s and Why’s of the Plan - A ‘Simple Guide’ to enhancing the glutathione/methylation cycles from Rich Van Konynenburg (Jan 2007)
- Treating Glutathione_Methylation Cycle Blockade Pt. II: the Treatment Plan – the in’s and out’s of the Simplified Treatment Plan
- Interpretation of the Methylation Pathways Panel – Rich explains how to interpret the Methylation Pathways panel
- Augmenting Glutathione Levels in CFS - The most extensive resource on the net of the many different ways used to boost the levels of this master antioxidant in the body. This has been superseded by Rich’s Methylation Cycle Treatment Plan.
VIDEO’S
THEORY PAPERS
- Glutathione and Chronic Fatigue Syndrome (ME/CFS) (2004) - Rich Von Konynenburg’s original paper in describes why he believes glutathione depletion plays a central role in ME/CFS; largely superseded by the Methylation Blockade Theory paper below.
- The Glutathione / Methylation Blockades in Chronic Fatigue Syndrome (ME/CFS) - A paper presented at the 2007 IACFS/ME Conference
- Methylation Cycle Blockade Theory - History and Underpinnings – How the Hypothesis came about, what it is, why the Yasko-Autism connection fits, and why he believes it pertains to ME/CFS (7/07)
- A Simpler Explanation of the Glutathione/Methylation Blockade Theory (12/08) - Rich provides a step by step simpler explanation of his theory
- Chronic Fatigue Syndrome and Autism - exploring possible connections between CFS and autism
- MethylationPPP- Download Rich’s powerpoint presentation to the 2008 Orthomolecular Health Medicine Society on Glutathione, Methylation and chronic fatigue syndrome
- Why is the Prevalence of CFS Higher in Women Than in Men? (2007)
4 comments
{ 3 comments… read them below or add one }
I’m very sorry to hear that Rich is dead. I corresponded with him extensively some years ago and his ideas on methylation and glutathione helped build my own understanding of Hepatitis C, where hypomethylation is a factor in liver degeneration and predicts a poor response to drugs. (HCV is of course one possible cause of CFS/ME, and the presence of the virus shouldn’t preclude a dual diagnosis).
Rich was very helpful and generous to someone struggling to understand.
This is a great summary of Rich’s work; I refer to it often. By the way, Rich’s last name is spelled wrong in the title – it says Von instead of Van.
Also, the title “Video’s” should not have an apostrophe. It should simply be “Videos”. Yes, the spelling and grammar police are out in full force today. lol
{ 1 trackback }